What Is Genicular Artery Embolization?
Genicular artery embolization, commonly referred to as GAE, is a minimally invasive interventional radiology treatment for knee osteoarthritis. Knee osteoarthritis, also known as degenerative arthritis, develops as cartilage within the knee joint gradually wears down, leading to inflammation, stiffness, and chronic pain.
In addition to cartilage loss, chronic inflammation plays a major role in knee osteoarthritis. Many patients with knee OA develop abnormal blood vessels within the joint capsule, which contribute to ongoing inflammation and pain. Genicular artery embolization targets these abnormal vessels.
During GAE, an interventional radiologist inserts a thin catheter into an artery in the upper thigh. Using real-time X-ray imaging, the catheter is guided to the genicular arteries, which are small arteries that supply the knee joint. Tiny particles called microspheres are then released to block abnormal blood flow. By reducing blood flow to inflamed areas of the knee, inflammation and pain are decreased.
Although reducing blood flow may seem counterintuitive, it specifically targets abnormal vessels associated with inflammation while preserving normal circulation.
Benefits of Genicular Artery Embolization
Minimally invasive treatment
GAE is a nonsurgical procedure that does not involve large incisions, bone removal, or general anesthesia.
Outpatient procedure
Patients typically go home the same day without the need for an overnight hospital stay.
Short procedure and recovery time
The procedure usually takes between 45 and 90 minutes, and most patients resume normal activities within a few days.
Long-lasting pain relief
Clinical studies show significant pain reduction for several months, with some patients experiencing relief for one year or longer.
Lower risk profile
Compared to open surgery, GAE carries fewer risks and fewer side effects, especially when compared to long-term medication use.
FAQ
1. Is genicular artery embolization safe?
Current research shows that genicular artery embolization is a safe procedure. Compared to open surgery, it carries a lower risk of bleeding, infection, and anesthesia-related complications. When side effects do occur, they are usually mild and may include temporary discomfort at the access site or bruising.
2. How effective is genicular artery embolization?
Clinical studies have shown that genicular artery embolization provides significant and long-lasting pain relief in approximately 70 percent of treated patients. Some studies report even higher success rates. Most patients experience few or no significant side effects following treatment.
3. How long do the results of genicular artery embolization last?
Pain relief from genicular artery embolization typically lasts between 6 and 12 months. Some studies have shown that certain patients experience continued pain relief for several years following treatment.
4. What should I expect during genicular artery embolization?
During the procedure, you will lie on a padded table and receive local anesthesia along with intravenous sedation. The interventional radiologist will guide a thin catheter from the femoral artery to the arteries supplying the knee using X-ray imaging. Tiny particles are then injected to block the abnormal blood vessels contributing to inflammation and pain. Usually, one to three arteries are treated during a single session.
After the procedure, a dressing is placed over the access site. Some patients may notice temporary skin discoloration around the knee in the days following treatment. If open sores or skin breakdown occur, you should contact your physician promptly.
5. What is the recovery like after genicular artery embolization?
Following the procedure, patients typically remain in the recovery area for about four hours. Most patients go home the same day and return to normal daily activities within two to three days. Mild discomfort around the knee or access site is common, and you will be instructed on how to care for the dressing during recovery.